TrumpRx Eligibility 2026: Who Qualifies, Who Doesn’t, and the Complete Drug Prices List

Y ou’ve seen the headlines. TrumpRx.gov is live. Wegovy for $149. Ozempic for $350. Fertility drugs slashed by 93%. And your first question — the only question that actually matters — is a simple one: Do I qualify?
Here’s the short answer: TrumpRx eligibility is more restricted than the press coverage suggests, and millions of Americans who think they’ll save money may be surprised to discover they don’t qualify at all — or that even if they do, a cheaper option already exists. But for the right patient, TrumpRx delivers real, life-changing savings on some of the most expensive medications in America.
This guide gives you the complete TrumpRx eligibility rules, the full drug prices list with before-and-after pricing, the income guidelines most articles are ignoring, and the critical restrictions that every patient needs to understand before clicking “get coupon.”
Read every section — because the eligibility detail that disqualifies most people is buried in rule number three, and skipping it could cost you hundreds of dollars at the pharmacy.
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What Is TrumpRx and Why Does Eligibility Matter So Much?
Launched on February 5, 2026, TrumpRx.gov is a federal government platform that aggregates discounted cash-pay pricing on 43 brand-name prescription medications from five participating pharmaceutical companies:
AstraZeneca, Eli Lilly, EMD Serono, Novo Nordisk, and Pfizer. Eleven additional drug manufacturers have signed Most-Favored-Nation (MFN) pricing agreements and will be added to the platform in the coming months.
Unlike a pharmacy or an insurance plan, TrumpRx doesn’t sell medications. It functions as a curated directory and coupon hub.
Displaying discounted prices and either providing downloadable coupons for use at participating pharmacies, or redirecting patients to the drug manufacturer’s own direct-to-consumer portal to complete their purchase. A valid prescription from a licensed physician is required for every medication on the platform.
Why does eligibility matter so much? Because TrumpRx’s restrictions are unusually strict — stricter than GoodRx, stricter than Cost Plus Drugs, and stricter than any standard pharmacy coupon program. Getting those rules wrong doesn’t just mean a failed transaction. It could mean losing insurance deductible credit for thousands of dollars in medical spending.
TrumpRx Eligibility: The 5 Rules You Must Meet
To access discounted pricing through TrumpRx, patients must meet every one of the following requirements. Failing even one disqualifies you from using the platform for that medication.
Rule 1 — You Must Be a U.S. Resident.
TrumpRx is available exclusively to patients residing in the United States. Non-residents and patients living abroad are not eligible, regardless of their citizenship status.
Rule 2 — You Must Pay Entirely in Cash.
TrumpRx is a cash-pay-only platform. This is the platform’s single most important restriction and the one that eliminates the largest number of potential users. The site itself states plainly: “At this time, TrumpRx discounted pricing is only available for cash-paying patients.”
You cannot split payment between cash and insurance, and you cannot submit a TrumpRx purchase for partial reimbursement from your insurer.
Rule 3 — You Cannot Be Enrolled in a Government-Funded Health Program.
This is the rule that disqualifies the most people — and the one most commonly overlooked in media coverage. Patients currently enrolled in Medicare, Medicaid, TRICARE, the VA healthcare system, or any other federally or state-funded prescription drug program are not eligible to use TrumpRx discounts.
You must attest — by clicking an acknowledgment button on the site — that you are not participating in any such program before a coupon or referral link will be generated for you.
Rule 4 — You Cannot Seek Insurance Reimbursement.
Even if you have private employer-sponsored insurance and technically choose to pay cash, you must agree that you will not submit your TrumpRx purchase to your insurance company for reimbursement of any kind.
This also means your TrumpRx spending does not count toward your annual insurance deductible or out-of-pocket maximum — a meaningful financial cost for anyone managing a chronic condition with ongoing prescription needs.
Rule 5 — Income Guidelines Apply for Maximum Discounts (Fertility Drugs).
For fertility medications under the EMD Serono agreement, the deepest discounts are reserved for patients earning below 550% of the Federal Poverty Level — approximately $115,000 annually for an individual in 2026.
Patients above this income threshold may still access some discounts on fertility drugs, but at a reduced rate compared to the maximum advertised savings.

Who TrumpRx Is Designed For — And Who It Isn’t
Understanding TrumpRx’s ideal patient profile makes it immediately clear who will benefit and who won’t. The platform is best suited for three specific groups.
The first group is uninsured Americans — the roughly 8% of the U.S. population with no insurance coverage at all. For these patients, TrumpRx represents a legitimate, government-backed alternative to paying full manufacturer list prices for brand-name medications.
The second group is patients with insurance that excludes specific drug categories. GLP-1 obesity medications like Wegovy and Zepbound are excluded from coverage by the majority of private insurance plans.
Fertility medications are similarly excluded by most plans. For patients in these categories who are otherwise insured, TrumpRx pricing can deliver significant real-world savings because there is no insurance benefit to compare against.
The third group is patients with very high deductibles who have not yet met their out-of-pocket maximum for the year and whose specific drug has no affordable generic equivalent. For this subset, the cash math sometimes favors TrumpRx — but only after carefully calculating the deductible credit they’ll lose by going outside their insurance network.
TrumpRx is not designed for — and delivers no benefit to — the approximately 84% of Americans who have comprehensive prescription drug coverage through employer insurance, Medicare Part D, or Medicaid. For this majority, standard insurance co-pays will almost always produce a lower out-of-pocket cost than TrumpRx’s cash prices.
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Trump Rx Drug Prices List (2026): All 43 Medications with Before and After Pricing
The table below shows every drug category listed on TrumpRx.gov at launch on February 5, 2026, with original manufacturer list prices, TrumpRx cash-pay prices, and the actual percentage saved. All prices reflect a one-month supply unless noted. Prices may vary by dosage strength. Always verify current pricing at TrumpRx.gov before purchasing.
| Drug Name | Manufacturer | Treats | List Price / Mo. | TrumpRx Price / Mo. | Savings |
|---|---|---|---|---|---|
| ► GLP-1 Weight Loss & Diabetes Medications | |||||
| Wegovy (injectable)semaglutide injection | Novo Nordisk | Obesity, Heart Disease | $1,349 | $199–$349$199 first 2 months; $349 after | Up to 85% off |
| Wegovy (pill/oral)semaglutide tablet | Novo Nordisk | Obesity | $1,349 | $149–$299 | Up to 89% off |
| Ozempicsemaglutide injection | Novo Nordisk | Type 2 Diabetes, Obesity | $1,028 | ~$350 | ~66% off |
| Zepboundtirzepatide injection | Eli Lilly | Obesity | $1,088 | $299–$449Via LillyDirect portal | Up to 73% off |
| Mounjarotirzepatide injection | Eli Lilly | Type 2 Diabetes | $1,069 | Varies by doseVia LillyDirect portal | MFN pricing |
| ► Fertility Medications (EMD Serono) | |||||
| Gonal-F 450IU penfollitropin alfa | EMD Serono | Infertility / IVF | $1,449 per pen | $252 per pen | 83% off |
| Gonal-F 300IU penfollitropin alfa | EMD Serono | Infertility / IVF | ~$966 per pen | $168 per pen | 83% off |
| Cetrotidecetrorelix | EMD Serono | Infertility / IVF | $316 | $22.50 | 93% off ★ |
| Ovidrelchoriogonadotropin alfa | EMD Serono | Infertility / IVF | $251 | $84 | 67% off |
| ► Diabetes Medications (Non-GLP-1) | |||||
| Januviasitagliptin | Pfizer | Type 2 Diabetes | ~$550 | ~$115 | 79% off |
| Jardianceempagliflozin | Pfizer / Boehringer | Type 2 Diabetes, Heart Failure | ~$660 | ~$37044% list price reduction applied | 44% off |
| Farxigadapagliflozin | AstraZeneca | Type 2 Diabetes, Heart Failure, CKD | ~$640 | MFN-aligned price | MFN pricing |
| ► Cardiovascular / Blood Thinners | |||||
| Eliquisapixaban | Pfizer / BMS | Blood Clots, Stroke Prevention, AFib | $245.48 | $122.74 | 43% off |
| ► Autoimmune & Inflammatory Conditions | |||||
| Xeljanztofacitinib | Pfizer | Rheumatoid Arthritis, Ulcerative Colitis, Psoriatic Arthritis | ~$4,500 | MFN-aligned price | 33% off |
| Eucrisacrisaborole | Pfizer | Eczema (Atopic Dermatitis) | ~$900 | MFN-aligned price | MFN pricing |
| ► Cancer / Oncology | |||||
| Imbruvicaibrutinib | Pfizer / J&J | Leukemia, Lymphoma (Blood Cancers) | ~$14,000 | MFN-aligned price | 38% off |
| ► Respiratory / Asthma / COPD | |||||
| Airsupraalbuterol/budesonide | AstraZeneca | Asthma (Rescue Inhaler) | ~$430 | Via AstraZeneca DirectRedirects to AZ patient portal | MFN pricing |
| Bevespi Aerosphereglycopyrrolate/formoterol | AstraZeneca | COPD | ~$560 | Via AstraZeneca Direct | MFN pricing |
| ► Mental Health / Antidepressants | |||||
| Pristiqdesvenlafaxine | Pfizer | Depression | ~$400 | ~$200⚠ Generic costs ~$16.65/mo via Cost Plus Drugs | ~50% off list |
| ► Gastrointestinal | |||||
| Protonixpantoprazole | Pfizer | Acid Reflux / GERD | $447 | ~$200⚠ Generic pantoprazole ~$30 via GoodRx | ~55% off list |
| ► Migraine | |||||
| Zavzpretzavegepant | Pfizer | Acute Migraine (Nasal Spray) | ~$1,000 | MFN-aligned price | MFN pricing |
| ► Vaccines & Preventive | |||||
| FluMistinfluenza vaccine (nasal) | AstraZeneca | Influenza Prevention | ~$30 | Discounted price | MFN pricing |
| ► Additional Pfizer Brand Medications | |||||
|
The following additional Pfizer brand-name medications are listed on TrumpRx at Most-Favored-Nation pricing. Exact cash prices vary by dosage strength and are updated in real time via the GoodRx API integration. Verify current pricing directly at TrumpRx.gov:
Ibrance (palbociclib — breast cancer) • Bosulif (bosutinib — leukemia) • Inlyta (axitinib — kidney cancer) • Sutent (sunitinib — kidney/GI cancer) • Lorbrena (lorlatinib — lung cancer) • Piqray (alpelisib — breast cancer) • Vyndaqel (tafamidis — cardiomyopathy) • Vyndamax (tafamidis meglumine — cardiomyopathy) • Nurtec ODT (rimegepant — migraine prevention) • Cibinqo (abrocitinib — eczema) • Litfulo (ritlecitinib — alopecia areata) • Padcev (enfortumab vedotin — bladder cancer) • Trazimera (trastuzumab — breast cancer) • Braftovi (encorafenib — melanoma) • Mektovi (binimetinib — melanoma) |
|||||
ⓘ Important Notes: (1) All prices are cash-pay only. TrumpRx does not accept insurance. (2) Purchases do not count toward your insurance deductible or out-of-pocket maximum. (3) Medicare, Medicaid, TRICARE, and VA beneficiaries are not eligible for TrumpRx cash-pay pricing. (4) About half the drugs on TrumpRx have generic equivalents available at significantly lower prices via GoodRx or Cost Plus Drugs — always compare before purchasing. (5) Prices marked “MFN-aligned” are verified through manufacturer agreements but exact dollar amounts update dynamically on TrumpRx.gov via GoodRx API. (6) ★ denotes the largest discount on the platform (Cetrotide at 93% off). ⚠ denotes drugs where a generic alternative is meaningfully cheaper.
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Can Medicare or Medicaid Beneficiaries Ever Use TrumpRx?
This is one of the most searched questions about TrumpRx eligibility, and the answer requires nuance. Standard TrumpRx coupons and direct-to-consumer discounts are not available to Medicare or Medicaid enrollees. These government program participants are explicitly excluded from the cash-pay attestation requirement.
However, the Trump Administration has separately negotiated MFN-aligned pricing for Medicare beneficiaries as a distinct track.
Under the Eli Lilly and Novo Nordisk agreements, eligible Medicare beneficiaries will pay a $50 monthly co-pay for the four key GLP-1 drugs — Ozempic, Wegovy, Zepbound, and the pending orforglipron — beginning mid-2026.
This Medicare pricing track is separate from TrumpRx.gov and will be administered through standard Medicare Part D plans, not through the TrumpRx platform itself.
State Medicaid programs will also access MFN-aligned pricing for these drugs, effective mid-2026, through separate state plan agreements. Again, this does not flow through TrumpRx.gov.

TrumpRx vs. GoodRx vs. Cost Plus Drugs: Which Saves You More?
Smart patients check all three platforms before filling any expensive prescription. Here’s how TrumpRx compares across the most relevant drug categories for cash-paying patients.
For GLP-1 medications, TrumpRx and the manufacturer’s own direct-to-consumer programs (LillyDirect, Novo Nordisk Direct) are essentially tied — TrumpRx consolidates access to these in one place. GoodRx typically does not match these prices for GLP-1 brand drugs. Cost Plus Drugs does not carry GLP-1 brand medications.
For fertility medications, TrumpRx is unambiguously the strongest option for uninsured patients, with Cetrotide at 93% off list price representing the most dramatic real-world saving on the entire platform.
For generic-eligible brand drugs (Protonix, Pristiq, and others in Pfizer’s portfolio), GoodRx and Cost Plus Drugs both produce significantly lower prices than TrumpRx, because TrumpRx lists only brand-name versions.
A patient comparing Pristiq on TrumpRx ($200/month) versus desvenlafaxine generic on Cost Plus Drugs ($16.65/month) is looking at a savings difference of more than $2,000 per year in favor of Cost Plus.
The practical takeaway: always check TrumpRx, GoodRx, and CostPlusDrugs.com side by side before filling any brand-name prescription out of pocket.
How to Check Your Eligibility and Use TrumpRx in 4 Steps
- Visit TrumpRx.gov and search for your medication. No account creation or login is required to browse and compare drug prices.
- Click the drug listing and review the eligibility attestation requirements displayed on that drug’s page. Each medication may have slightly different restrictions based on the manufacturer’s agreement.
- Complete the eligibility attestation by confirming you are a U.S. resident, not enrolled in a government-funded health program, and will not seek insurance reimbursement. This step generates your coupon or referral link.
- Redeem your coupon at a participating pharmacy, or follow the link to the manufacturer’s direct-to-consumer portal (such as LillyDirect for Eli Lilly drugs or Novo Nordisk’s patient portal for Wegovy and Ozempic) to complete your order with a valid prescription.
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Frequently Asked Questions About TrumpRx Eligibility
Who is eligible for TrumpRx discounts?
TrumpRx eligibility requires that you are a U.S. resident, pay entirely in cash without using insurance, are not currently enrolled in any government-funded health program (including Medicare, Medicaid, TRICARE, or VA benefits), and agree not to seek insurance reimbursement for your purchase. Patients with private employer insurance may technically use TrumpRx, but must waive all insurance reimbursement rights and lose deductible credit for the purchase.
Can I use TrumpRx if I have Medicare or Medicaid?
No. Standard TrumpRx cash-pay discounts are not available to Medicare or Medicaid enrollees. However, Medicare beneficiaries will gain access to MFN-aligned GLP-1 drug pricing through standard Medicare Part D plans starting mid-2026, at a maximum $50 monthly co-pay — administered separately from the TrumpRx.gov website.
Is there an income limit to qualify for TrumpRx?
For most TrumpRx medications, there is no income limit. Any cash-paying U.S. resident who meets the insurance restrictions can access the discounts. However, for EMD Serono fertility medications, the deepest discounts are reserved for patients earning below 550% of the Federal Poverty Level — approximately $115,000 annually for an individual in 2026. Patients above this threshold may still qualify for reduced (but smaller) discounts on fertility drugs.
Does spending on TrumpRx count toward my insurance deductible?
No. Purchases made through TrumpRx using cash-pay pricing do not count toward your health insurance deductible or out-of-pocket maximum. This is a critical financial consideration for patients managing chronic conditions with ongoing prescription costs, as bypassing your insurance deductible each month could significantly increase your total annual healthcare spending.
What drugs are on the TrumpRx drug prices list?
As of February 2026, TrumpRx lists 43 brand-name medications from AstraZeneca, Eli Lilly, EMD Serono, Novo Nordisk, and Pfizer. These include GLP-1 obesity drugs (Wegovy, Ozempic, Zepbound), fertility medications (Gonal-F, Cetrotide, Ovidrel), diabetes drugs (Januvia, Jardiance), blood thinners (Eliquis), and numerous Pfizer brand-name medications across multiple conditions. Additional drugs from 11 other manufacturers are expected to be added in the coming months.
Can I use TrumpRx with private insurance?
Technically yes, if you have private employer-sponsored insurance rather than a government program. However, using TrumpRx means paying the full cash price out of pocket, forfeiting insurance reimbursement, and losing deductible credit for that spending. For patients with insurance co-pays below the TrumpRx cash price — which is the majority of insured patients — it will be less expensive to use your insurance. The exception is drugs not covered by your plan, such as GLP-1 obesity medications or fertility drugs.
How do I know if TrumpRx is cheaper than my insurance co-pay?
TrumpRx itself advises users to check their insurance co-pay first. To compare: call your pharmacy and ask for your co-pay amount for the specific drug and dosage under your current insurance plan. Then compare that figure to the TrumpRx cash price listed on the site. If your co-pay is lower, use your insurance. If the TrumpRx cash price is lower — most likely for uncovered drugs like GLP-1s or fertility medications — TrumpRx may save you money. Also compare against GoodRx and Cost Plus Drugs before deciding.
Medical Disclaimer
The information provided in this article is for educational purposes only and is not intended as medical advice. Always consult your healthcare provider before starting any new dietary supplement, especially if you have a medical condition or are taking prescription medication.
Sources and Medical References
- White House Official Fact Sheet: President Donald J. Trump Launches TrumpRx.gov — whitehouse.gov
- STAT News: What to Know About TrumpRx, the Trump Administration’s Prescription Drug Platform (February 5, 2026) — statnews.com
- Fertility Centers of New England: TrumpRx Is Here — What the Federal Program Means for Fertility Medication Costs — fertilitycenter.com
- NPR: TrumpRx Drug Prices and Discounts Explained (February 5, 2026) — npr.org
- Pharmaceutical Commerce: TrumpRx Launches With MFN-Based Drug Discounts — Eligibility and Access Details — pharmaceuticalcommerce.com
- PharmExec: “TrumpRx Is Live and Complicated” (February 6, 2026). Available at: https://www.pharmexec.com/view/trumprx-is-live-complicated
- Pharmacy Times: “TrumpRx Launches, Offering Cash-Paying Patients Discounted Drugs” (February 6, 2026). Available at: https://www.pharmacytimes.com/view/trumprx-launches-offering-cash-paying-patients-discounted-drugs
- TrumpRX.gov: “Ozempic Pen Eligibility Terms” (Accessed February 2026). Available at: https://trumprx.gov/p/ozempic
- The White House: “Fact Sheet: President Donald J. Trump Launches TrumpRx.gov to Bring Lower Drug Prices to American Patients” (February 5, 2026). Available at: https://www.whitehouse.gov/fact-sheets/2026/02/fact-sheet-president-donald-j-trump-launches-trumprx-gov-to-bring-lower-drug-prices-to-american-patients/
- NerdWallet via SFGATE: “Will TrumpRX Help You Save? It Depends” (February 10, 2026). Available at: https://www.sfgate.com/business/personalfinance/article/will-trumprx-help-you-save-it-depends-21345801.php
